who should not take semaglutide for weight loss Avoid Semaglutide: Medical Contraindications Semaglutide has become one of

Mol Cell Biochem 481 , 911922 (2026)

This classifies it as a glucagon-like peptide-1 (GLP-1) receptor agonist

Fact: The active ingredient, semaglutide, is what provides the metabolic benefit

But it cannot replace: consistent meal structure adequate protein intake fibre from whole foods micronutrient sufficiency stable blood sugar patterns reduced inflammatory food exposure Metabolism is built through daily behaviour

One study published in 2025 in Diabetologia looked at whether taking GLP-1 drugs were associated with worsening of retinopathy when patients had no or only mild nonproliferative diabetic retinopathy (NPDR) at initiation of treatment