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A deeper knowledge of their broad effects can optimize their therapeutic use in treating conditions like type 2 diabetes, obesity, and heart disease, while minimizing side effects and improving patient care
The analysis showed that in the later stages of in vitro islet cell differentiation, FGFR1 was highly expressed in pancreatic endocrine cells, including alpha cells, beta cells and neurogenin 3-positive pancreatic endocrine progenitors (ESM Figs 4 and 5), suggesting that FGF21 might exert an effect on endocrine pancreas
Lay out every piece of equipment before touching anything else
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This reflects improved symptoms, quality of life, and delayed progression to worsening heart failure, rather than a clear mortality benefit
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