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Semaglutide is substantially superior to exenatide in weight loss efficacy (14.9% vs 2-4%), glycemic control (SUSTAIN 3 head-to-head), cardiovascular outcomes (proven superiority vs non-inferiority only), and dosing convenience (pre-filled weekly pen vs reconstitution)
doi: 10.1016/j.bbrc.2007.07.088 35 GengJ.LiuW.GaoJ.JiangC.FanT.SunY.et al
What if I hit a plateau on GLP1 meds
Zhai et al., 2013)
Understanding Semaglutide Dose Ceilings and Safety Limits The maximum approved semaglutide dose of 2.4 mg weekly was established through clinical trials measuring both efficacy and tolerability across diverse patient populations
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