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Real-world results vary based on starting weight, adherence, diet quality, physical activity, and individual metabolism

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This discovery also paved the path to additional GLP-1 agonists, like tirzepatide , a dual agonist that targets both GLP-1 and GIP receptors for even greater metabolic impact

To date, bariatric surgery remains the most effective way for substantial long-lasting weight loss in severe obesity

Stay well hydrated, especially during the first few weeks