semaglutide and cardiovascular outcomes in obesity without diabetes patients with and prevalent heart failure: a prespecified analysis of the SELECT trial Effects of Semaglutide on Cardiometabolic

Aly-Aly concluded that treating obesity and metabolic syndrome with GLP-1s is likely to have broad benefits that extend beyond just reducing BMI or reducing weight, while the drugs hold promise for addressing other diseases.

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This distinction is crucial for individuals with cardiovascular concerns, as PT-141s mechanism does not directly impact cardiovascular function or blood pressure so is considered less risky than Viagra (3)