NNMT slows down fat cell metabolism (which makes losing weight even more difficult.) By blocking NNMT, 5 Amino 1MQ can prevent this metabolism slow-down and promote weight loss
Evidence boundary The largest Phase 2b trial used oral dosing for 24 weeks and did not show statistically significant weight loss versus placebo
No human half-life has been established
Tirzepatide Weight Loss Support in California, Oregon, and Washington At Flow Wellness, we help patients understand every aspect of their GLP-1 treatment program, including medication dosing, side effect management, nutrition, and long-term success strategies
In the STEP-1 semaglutide trial, roughly 39% of the weight lost was lean mass in the DEXA substudy ( Wilding et al., NEJM 2021 )