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Khurana A
120 mg/kg)
302,303,304,305 GLP-1R signaling, through PKA, inhibits this process, possibly by promoting IB stability or inhibiting its phosphorylation, thus reducing NF-B activation and nuclear translocation
Clinical trials have shown promising results, with participants on a 12-mg dose achieving an average weight loss of 24.2% after 48 weeks
[10] It is worth noting that gastrointestinal side effects nausea, vomiting, and diarrhoeaare common with Saxenda, particularly during dose escalation
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