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6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase (PFKFB3 is a key glycolytic regulator upregulated by disturbed flow, promoting EC proliferation, inflammation, and angiogenesis, while laminar shear stress suppresses its expression to maintain EC quiescence [35, 38, 42, 44, 56, 202, 220]
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When CJC-1295 is injected, it binds to the growth hormone-releasing hormone (GHRH) receptors, mimicking its function to stimulate the pituitary gland to release more GH
& Padilla, J
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