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Saiki and colleagues identified marker genes for the differential diagnosis of CFS i.e., the expression of GZMA , PSMA3 , PSMA4 , COX5B , ATP5J2 , and DB1 was decreased while the expression of STAT5A was upregulated in CFS individuals (Saiki et al

Spiering BA, Kraemer WJ, Vingren JL, Hatfield DL, Fragal MS, Ho JY, Maresh CM, Anderson JM, Volek JS

doi: 10.1007/s00418-020-01858-w 42

Until such studies are conducted, the combination remains investigational and should be approached with appropriate caution, written informed consent, and consideration of FDA MedWatch reporting for any adverse events that occur with off-label combination use

The GLP-1 Booster is heavy on plant alkaloids and extracts, with the main star Berberine