The FDAs crackdown in the United States should serve as an immediate warning to Brazil: clinics and compounding pharmacies that persist in illegal practices substituting industrialized medicines with compounded ones, improperly using registered trademarks, and engaging in irregular dispensing activities must be held accountable
Multifunctional nanoplatforms are most valuable when these barriers are translated into clear design objectives, including improved tumor access and retention, vascular and stromal normalization, TME-responsive release or activation, immune priming or intratumoral reprogramming, and imaging-guided treatment planning
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Race, ethnicity, age, treatment type, and functional status were associated with submission in the multivariable analysis
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