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In the STEP trials, semaglutide produced average weight loss of 1518% at the 2.4 mg maintenance dose, with approximately 80% of participants achieving clinically significant (5%) weight loss
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Drug Discov 6 , 904916 (2007)
Some providers will prescribe GLP-1 medications for patients whose BMI falls slightly below the 27 threshold if there is strong clinical justification
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