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In parallel, advances in peptide chemistry and structural biology have enabled the design of aggregation inhibitors, receptor-selective neuropeptide analogues, and cell-penetrating or brain-targeted peptide conjugates that modulate key pathways, including proteostasis, insulin and incretin signaling, neurotrophic support, and microglial activation
Nichols DJ, Muirhead GJ, Use JA
These GLP1 therapies were originally developed for metabolic regulation, specifically for glucose control in people with type 2 diabetes, she explains
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