These can often be managed with simple measures (e.g., analgesic for headache, proper injection technique for site pain)
A 2020 retrospective analysis of 4,217 patients on concurrent ARB and systemic corticosteroid therapy found that systolic blood pressure rose by a mean of 8.4 mmHg within 14 days of corticosteroid initiation, compared to 1.2 mmHg in matched controls receiving ARBs alone [3]
The practical upshot is that the anti-inflammatory effect seems to operate even at low doses what clinicians increasingly call microdosing, which Ill return to below
We know this from food safety the categories with the weakest audit culture are consistently the ones where quality failures cluster
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