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In trials, retatrutide showed somewhat higher weight loss (~28.7% vs ~22.5%) and much higher liver fat reduction

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Monotherapy with MOUNJARO 5 mg, 10 mg and 15 mg once weekly for 40 weeks resulted in a statistically significant reduction in HbA1c compared with placebo (see Table 4)

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In simple terms, it signals the pituitary gland to release more growth hormone (GH) into the bloodstream

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Similarly, Randall Turner, DO, medical director at Able2Change says side effects typically occur when you first initiate Zepbound treatment or when you change the dose, and digestive side effects subside over a few days to weeks as the body adjusts

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Contrave contains naltrexone (an opioid antagonist) and bupropion (an antidepressant)

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