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Admittedly, the available evidence is of variable quality, and it is hard to compare the studies because different experimental approaches, doses, administration schemes, and so on, have been applied
Cell 177 , 19331947 (2019)
On the cardiovascular side, the SUSTAIN-6 trial in 2016 was one of the first to report a significant reduction in major adverse cardiovascular events with semaglutide in adults with type 2 diabetes and high cardiovascular risk (Marso et al., NEJM, 2016)
The HRTS portfolio aims to be broadly exposed to breakthrough innovation and to balance risk profiles
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