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Its key advantage is high specificity for GH release without triggering ACTH or cortisol elevation, making it one of the safer GH secretagogues with minimal off-target hormonal effects [1] [3]

A comprehensive review of the role of biologics and small-molecule therapies in the long-term management of Crohns disease

Kadowaki, "Effects of lactulose on renal function and gut microbiota in adenine-induced chronic kidney disease rats", Clinical and Experimental Nephrology