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PMID 29364588 Nauck MA et al
The most effective relief comes from a combination of hitting 25 to 35 grams of fiber daily, drinking at least 73 to 100 ounces of water, staying physically active, and using an osmotic laxative like MiraLAX when dietary changes are not sufficient
Preclinical and observational evidence, as well as some small studies, suggested potential benefits of GLP-1 agonists, but this large trial does not confirm clinical efficacy in early Alzheimers. Have the authors taken confounding factors into account
About 12% say theyve tried GLP-1 drugs, like Ozempic, Wegovy or Zepbound, with rates of use highest among people ages 50 to 64, survey results show
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