NICE Technology Appraisal 875 (Wegovy) and TA664 (Saxenda) recommend these treatments within specialist tier 3 or 4 weight management services for adults with a BMI of 35 kg/m or above (or 32.5 kg/m or above for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family backgrounds), with weight-related comorbidities
Its unclear how such a treatment would react with adenosines immunostimulatory, primarily anti-inflammatory, effects in distinct immune cell types, 152 or how elevated DPP4 activity and prolonged subclinical inflammation in obesity-induced MS would impact the therapeutic outcome
Who should consider GLP-1 supplements Not everyone needs a GLP-1 supplement
While commonly found in foods of animal origin and fortified foods, many suffer from vitamin B-12 deficiency due to a low absorption rate or vegan diet
Always remember, talking to your own doctor is the most important step for any questions you have about your medicine