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By weeks 3-4, users following a consistent caloric deficit may notice subtle changes: slightly looser-fitting clothing around the midsection, a minor reduction in waist measurement (0.5-1 cm), and potentially 0.5-1 kg of fat loss on top of what diet alone would produce

Mol Psychiatry (2021) 26:430014

It is an unapproved investigational compound that did not complete clinical development, has not been authorized by Health Canada for any human or veterinary indication, and is not intended to diagnose, treat, cure, or prevent any disease

Individuals seeking to support fat metabolism and body composition under medical supervision may be candidates

At 12 weeks, repeat serum copper, ceruloplasmin, and renal function