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Experiments on mice have revealed that polystyrene microplastics damage the intestinal barrier and reduce intestinal mucus production [2, 25]
AREG and EREG are also crucial ligands for EGFR and play a key role in hepatocyte proliferation (Komurasaki et al., 2002
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For example, a methylene-linked oxetane increased potency 100-fold relative to the methyl substituent of 5 , leading to the identification of PF-06882961, which is a full agonist (EC 50 = 13 nM) in the CS cAMP assay (Fig
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