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Tirzepatide receptor pharmacology and predicted receptor occupancy GIPR-forward dual-incretin design, cAMP-biased GLP-1R with low beta-arrestin, GCGR negative control (EC50 329 nM)
Phase Reta escalation 1 Weeks 5-8 Retatrutide 4 mg/week Cagrilintide Not started Notes Continue retatrutide alone
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