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Suggestive as these changes clearly are, they likely represent only a small minority of the full breadth of pathogenically relevant changes in this dataset, many of which may involve proteins with as-yet poorly explored functions

Across clinical trials and real-world settings, weight loss remained modest, relapse rates after discontinuation were high, and treatment was often fragmented, lacking integration into interdisciplinary care models

10.1210/er.2013-1121 96 TrujilloJ

We did not observe a difference in blood glucose changes in response to our alcohol challenge drink, which contained sugars in both the vodka and mixers