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In addition, insulin-like growth factor-1 (IGF-1) treatment can inhibit CSD and calcitonin-gene-related peptide (CGRP) production, thereby relieving migraine-related hyperalgesia [29]
Retatrutide is a 39-amino-acid triple agonist peptide (GLP-1, GIP, and glucagon receptors) that produced 28.7% body weight loss in Phase 3 trials (Lilly Press Release, Dec 2025)
Patients should contact their healthcare professional if they experience persistent gastrointestinal symptoms, signs of pancreatitis, unexplained weight loss beyond expected, new or worsening vision problems, or any concerning symptoms
Which of the following is true regarding the mentation domain of the Age-Friendly 4Ms Framework
Another thing that's fascinating about the GLP-1 is its effect on epigenetic clocks
