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Confirmatory secondary endpoint: Change in body weight from baseline to Week 26
This data-driven framework prioritizes therapies within the DM2-AD comorbidity network, providing a strategy to identify drugs with the highest potential for reducing AD risk in DM2 patients
L-Carnitine supplementation an lead to improvements in several complications seen in uremic patients, including cardiac complications, impaired exercise and functional capacities, muscle symptoms, increased symptomatic intradialytic hypotension, and erythropoietin-resistant anemia through normalizing the reduced carnitine palmitoyl transferase activity in red cells [43]
Westermark P, Sletten K, Johansson B, Cornwell GG
It has shown significant efficacy in individuals with a BMI of 30 or higher, or 27 or higher with a weight-related condition, offering an average weight reduction of 15% over 68 weeks
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