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Optineurin suppresses mtROS-regulated NLRP3 inflammasome activation by upregulating mitophagy in HG treated TECs (151)
Meanwhile, overall aging indicators were significantly improved: locomotor activity and endurance were enhanced, hair gloss increased, levels of aging-related inflammatory factors (such as TNF-, IL-6) decreased, and the average lifespan of mice was prolonged
For CrossFit athletes dealing with systemic inflammation from chronic high-intensity training, this has a compounding benefit -- it does not just help the specific injury, it reduces the overall inflammatory load that slows recovery across the board
Individual results are not guaranteed and may vary from person to person
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