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When tissues such as muscle, liver, and fat no longer respond effectively to insulin, glucose remains in the bloodstream, increasing the risk of type 2 diabetes, obesity, and cardiovascular disease. This connection between estrogen and insulin resistance has sparked interest in how hormone replacement therapy (HRT) may work synergistically with modern weight loss therapies, particularly glucagon-like GLP-1 receptor agonists and glucose-dependent insulin tropic polypeptide (GIP) receptor/GLP-1 receptor agonist combos
HUBERMAN: Now, when we say positive effects, we have to stand back and say, well, what's the control experiment
May also aid in the treatment of obesity and chronic weight management in adjunction to a reduced calorie diet and increased physical activity
In many medical trials, Tirzepatide has outperformed Semaglutide for the amount of weight loss it facilitates
Exercise caution when using them together
