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Some evidence involving calcium homeostasis and apoptotic proteins in mitochondrial dysfunction has been reported in bipolar depression
doi: 10.3390/molecules27061821 167 WojdyoAOszmiaskiJ
Estrogen has been shown to upregulate endogenous MOTS-c expression in preclinical models, which may partly explain why metabolic deterioration accelerates in perimenopause when estrogen falls precipitously [2]
Taking amounts may lead to adverse effects such as feeling lightheadedness or headaches along with increased anxiety and the possibility of experiencing nausea and vomiting
More studies are still required to understand its efficacy in the long term
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