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A multifunctional poly(amino acid) nanomedicine (PM-DPA/R848) has been developed that encapsulates the TLR7/8 agonist resiquimod (R848) within a nanocarrier composed of poly(L-methionine) and alendronate-functionalized DSPE-PEG ( Calcium carbonate (CaCO3)-based nanosystems have been engineered to simultaneously neutralize the acidic TME and reprogram TAM polarization

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22lbs GONE ON 2.5-1st month

In the 8-mg groups, participants that received an initial dose of 2 mg lost 16.7% and 17.9% when treated with an initial dose of 4 mg, while the 12-mg group lost 17.5%

Pegylated liposomal doxorubicin (PLD