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Trends Endocrinol Metab 31:410421 Sassin AM, Sangi-Haghpeykar H, Aagaard KM, Detti L (2023) Effects of metformin alone versus metformin and tirzepatide on weight loss in patients with polycystic ovarian syndrome (PCOS)
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Although glucose is the principal energy fuel of the brain in normal conditions, lactate can be an alternative source during hypoglycemia and because of mitochondrial shifts in redox state or ischemia
A temporary plateau alone does not determine whether a dose increase is appropriate
You can discuss with your prescriber the potential side effects of the medication and weight-related changes while you are on personalized semaglutide therapy
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