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There is also debate as to the best delivery system, whether liposomal, oral, or intravenous
[cited 2016]
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Additionally, for individuals who cannot tolerate full therapeutic doses of metformin due to side effects, adding inositol might allow for lower metformin doses while maintaining some metabolic benefits, though this approach requires medical supervision
CT-996 was originally developed by Carmot Therapeutics, which Roche acquired in December 2023 for $2.7 billion upfront
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