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Copper also contributes to enzymes involved in connective tissue formation, antioxidant protection, pigmentation, and tissue maintenance

Injecting cold solution, injecting too rapidly, or using a dull needle all increase pain regardless of site

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A 2021 comparative bioavailability study found subcutaneous copper peptide administration achieved mean plasma AUC (area under the curve) values 1.6 higher than IM at equivalent doses, despite lower Cmax