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Preclinical studies have shown promising results: Specific strains such as Bifidobacterium breve and Lactobacillus plantarum reduce microglial activation, increase anti-inflammatory cytokines like IL-10, promote neurogenesis, and enhance cognitive performance in rodent models of AD [624, 625]

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Although much remains to be discovered, the primary theoretical pathway through which Parkinsons disease spreads was hypothesized by Braak and colleagues (Braak et al., 2003)