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Cross-sectional studies have shown that plasma and tissue glutathione concentrations decrease by approximately 10-15% per decade after age 45, and this decline is accelerated in conditions associated with chronic oxidative stress, including type 2 diabetes, cardiovascular disease, neurodegenerative diseases, HIV/AIDS, chronic liver disease, and chronic obstructive pulmonary disease (COPD) [2][3][10][11]
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With heart disease being the leading cause in death for women in the US, its essential for clinicians to support and educate women on hormonal and non hormonal methods for peri/menopause management, including options to reduce risk CVD, such as GLP-1 RAs
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