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These agents mitigate muscle atrophy by downregulating atrophy-related factors (myostatin, MuRF1, MAFbx) and upregulating myogenic transcription factors (MyoD, MyoG) via PKA/Akt/mTOR signaling

L-carnitine supplementation significantly improved LVEF (MD = 1.64, 95% CI 0.103.17, p = 0.04), with low heterogeneity ( I 2 = 37%)

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury

But strategic combinations can cover the inflammatory, barrier, and antimicrobial aspects of the disease