What excites me here isnt just AI in drug discovery, its what this could mean downstream for clinical trials: Better target selection before first-in-human studies
However, without robust clinical data, it's unclear whether they perform closer to injectable or oral tablets in real-world use
Lee GY, Lee JW, Lee E, Yeom JS, Kim KJ, Shin HI, et al
The AAFPs evidence-based clinical review states directly: Oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms in patients with B12 deficiency (Langan RC, Goodbred AJ, American Family Physician, 2017)
Side effects are primarily gastrointestinal, including diarrhea, constipation, and abdominal discomfort, ironically similar to GLP-1 medications but much milder