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Direct Drug Effect: While less understood, the direct pharmacological action of Ozempic on GLP-1 receptors in the central nervous system may also contribute to feelings of fatigue

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Patients with pre-existing gallbladder sludge or small asymptomatic gallstones detected on imaging may be at higher risk for progression to symptomatic disease during treatment

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GLP-1 and GLP-1/GIP medicines can be prescribed for weight management in people without diabetes, as long as medical criteria such as BMI and weight-related health conditions are met