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GLP-1 is an incretin hormone produced in the gut that enhances insulin secretion in response to food intake while suppressing glucagon, slowing gastric emptying, and reducing appetite ( [1] ) ( [2] )
8 As a result, the remainder of this review focuses on GLP-1
If you experience those, seek care immediately
All we're proposing to clinicians is Hey, think about the patients who are at risk and have a strategy to monitor and mitigate that risk. What about patients on GLP-1s
Seven additional Phase 3 trials are expected to complete in 2026, potentially positioning retatrutide as the next major obesity therapy
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