Kojic acid works externally by targeting pigmentation on the skin surface, while glutathione works internally by helping regulate melanin production and reducing oxidative stress, promoting long-term skin health
and it provides antioxidant protection that reduces oxidative stress-induced hyperpigmentation
Glutathione Morning intake allows detoxification and protection to the cell throughout the day
You will want to use 2-4 GRAMS per day to get this benefit, which means 2,000 to 4,000mg of high-quality fish oil per day (more info below)
Regarding mitochondrial dysfunction involved in AD pathophysiology, it includes disturbances in oxidative phosphorylation (OXPHOS), and impaired energy metabolism as well as excess generation of ROS, altered mitochondrial biogenesis, transport and dynamics (68)