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Important safety questions include product purity, dose accuracy, drug interactions, liver and kidney considerations, blood sugar changes, cardiovascular risk, pregnancy or breastfeeding status, and long-term exposure
Most studies did not identify postmenopausal women separately, and some cohorts had more men than women
Putting the trial numbers into perspective Historically, anti-obesity drugs produced average weight losses in the single digits (510%), and even the best options rarely approached double-digit percentages at the population level
Gastrointestinal (GI) issues The most frequently reported GLP-1 side effects impact the digestive system, especially during the first few weeks of therapy or after dose increases
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