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Extracellular adenosine can be transported into cells as a function of a concentration gradient where it is phosphorylated to AMP by adenosine kinase or degraded to inosine by ADA

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To examine the extent to which the phenotypes observed were specifically caused by lower GSH levels, we rescued GSH depletion in liver-specific Gclc KO mice with GSH mono ethyl ester (GSH-ee)