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Liver Protection: NSAIDs can induce liver damage and impair liver function
The 28-day mark is not a chemical cliff, and a vial punctured twice with good technique is not meaningfully different on day 30 than on day 27
10.1016/0896-6273(93)90281-u Neuron 113 MagaviS
This reduces their toxicity and maintains a proper balance of reactive oxygen species and antioxidants (or redox balance)
Body composition and histology DXA or EchoMRI for lean/fat mass, adipocyte morphometrics, and liver Oil Red O or lipidomics form a phenotypic core
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