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The DMF itself contains the suppliers complete process description: synthetic route, reagent specifications, solvent use, reaction conditions, purification methodology, analytical method specifications, stability protocols, and impurity profiling data

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The glycan chain at Asn297 was trimmed using the endoglycosidase Endo S2 and then azide groups were introduced using a mutant galactosyl transferase GalT(Y289L) and N -azidoacetylgalactosamine (GalNAz)

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