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Improved biological activity of Gly^ 2-and Ser^ 2-substituted analogues of glucose-dependent insulinotrophic polypeptide
A significant milestone to bring in the new year, the FDA approved Wegovy (semaglutide) on Dec
427,428,429 The compound NLY01 is particularly effective at attenuating the activity of proinflammatory microglia and preventing the transformation of astrocytes to a reactive phenotype
Biased Agonism: The concept of biased agonism - where a drug preferentially activates one signaling pathway over another - is a relatively new area in pharmacology
TMAO and Cholesterol Metabolism TMAO plays a key regulatory role in lipid metabolism ( Figure 1C )
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