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Siamashvili, M

Genetic variation in GLP-1 receptor structure (rs6923761), GLP-dependent insulinotropic polypeptide signaling (GIPR rs1800437), and metabolic regulators like FTO (rs9939609) influence both drug efficacy and side effect severity

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First, GLP-1 receptors are found not only in the pancreas and gastrointestinal tract but also in various other tissues throughout the body, raising theoretical questions about how chronic stimulation of these receptors might affect cell growth