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For example, clinicians might consider adjusting titration schedules in individuals with severe baseline retinopathy or extremely elevated A1C levels

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There is no statistically significant increase in the incidence of pancreatitis compared to placebo, according to extensive meta-analyses of randomized controlled studies (Dankner et al

People who are otherwise healthy may be less willing to accept these potentially serious adverse events. Initially designed to treat Type 2 diabetes, GLP-1 agonists witnessed a surge in usage as an alternative weight loss solution, amassing around 40 million prescriptions in the U.S

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