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GLP-1 is a 30 amino acid-long peptide hormone mainly produced in the intestinal L-cells of the gut that is secreted into the blood ( Figure 1 ) (Habib et al., 2013
In the SURMOUNT-1 trial, patients lost an average of 22.5% of body weight over 72 weeks
Therefore, collectively, these studies imply that these antioxidant strategies are not effective in ALS
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Additionally, in spinal cord ischemia-reperfusion injury and acute myocardial infarction, LC treatment diminished inflammation and oxidative stress while improving neurological and cardiac functions
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