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The drug is mainly evaluated due to its ability to affect the action of the melanocortin receptors, especially MC3R and MC4R, which are essential in signaling, neuroendocrine function and behavioral physiology

[5] [6] Durante el tratamiento, pueden surgir desequilibrios de electrolitos principalmente debido a efectos secundarios gastrointestinales y cambios en la ingesta alimentaria

inferred from weight-loss magnitude and class data Testosterone effect in men / weight loss of 10%+ raises free testosterone by roughly 2 to 3 nmol/L in prior obesity trials SHBG change / adiposity reduction consistently raises SHBG, increasing bioavailable androgens Women / fat-mass loss of this magnitude can restore LH pulsatility and ovulatory cycles in hypothalamic amenorrhea PCOS relevance / GLP-1-class agents reduce androgen excess and improve menstrual regularity Cardiovascular link / erectile dysfunction shares endothelial risk factors

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