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Black Box Warning Mounjaro carries an FDA-mandated black box warning regarding the risk of thyroid C-cell tumors observed in animal studies

This is significant because the approved versions of these medications explicitly state "Do not freeze and do not use if it has been frozen." Freezing can damage peptide structures, potentially reducing potency or altering the compound in ways that affect both efficacy and safety

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Eyeglasses do not help because NAION is related to nerve damage that is usually considered permanent

Key Differences: Ozempic vs