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Transient stress or increased cytoplasmic TDP-43 triggers phase separation into toxic cytoplasmic droplets that block nuclear import, deplete nuclear TDP-43, and cause cell death, offering a present mechanistic model for ALS/FTD pathology (Gasset-Rosa et al., 2019)

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The same excitement you might get from, Ooh, Im going to eat this pizza later, or Ooh, Im going to see my friend later, youre dampening this anticipatory response

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What the Health Canada notice says The Ottawa-issued notice, dated April 28, 2026, states that the first authorized generic semaglutide injection was the submission filed by Dr