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Nir Barzilai at the Albert Einstein College of Medicine and the American Federation for Aging Research (AFAR)

There may also be some thinning at the crown

Their comparison illustrates the two dominant strategies in modern obesity pharmacotherapy: combination therapy with proven agents versus novel single-molecule multi-agonism

Metabolic intervention may eventually be the most elegant way to manipulate the energy sensor mTORC1, which is critically involved in misleading T cells and turning them into multiplying and self-aggressive effector cells

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